This handbook documents the traditional medicinal plants used by the Sidama people in Ethiopia, providing botanical descriptions, therapeutic uses, preparation methods, and cultural practices associated with treating various ailments. Serving as both a repository of indigenous knowledge and an educational tool, it aims to support the integration of traditional medicine into local healthcare systems. The content is enriched with numerous high-resolution photographs of medicinal plants, their parts, and preparation processes, offering detailed coverage of plant-based remedies for common and culturally significant diseases, along with practical applications and pharmacological insights.